Sunday, 5 June 2016

Predicting cell behaviour with a mathematical model


Physicists have developed new software for the life sciences. The software supports the evaluation of microscope-based observations of cell behaviour on micropatterned substrates.

The software supports the evaluation of microscope-based observations of cell behaviour on micropatterned substrates. One example is a model for wound healing in which skin cells are required to fill a gap. Other areas of application lie in high throughput screening for medicine when a decision needs to be taken automatically on whether a certain active substance changes cell behaviour. Prof. Dr. Ulrich Schwarz and Dr. Philipp Albert work both at the Institute for Theoretical Physics and at the Bioquant Centre of Heidelberg University.

For further details see:

Philipp J. Albert, Ulrich S. Schwarz. Dynamics of Cell Ensembles on Adhesive Micropatterns: Bridging the Gap between Single Cell Spreading and Collective Cell Migration. PLOS Computational Biology, 2016; 12 (4): e1004863 DOI: 10.1371/journal.pcbi.1004863



Posted by Dr. Tim Sandle