Monday, 11 July 2016

Serotyping and genotyping methods for Chlamydia trachomatis

A new article of interest has been published:

Knowing prevalent sexually transmitted bacterial infections, we can mention Chlamydia trachomatis as one of the most important. For the purpose of the study, the genotyping methods have some advances being more precise, compared to immunotyping. In this context, the present study aims to compare phenotypic and genotypic methods for subspecies identification of Chlamydia trachomatis in term of discriminatory power and concordance. For analysis, a data table of Chlamydia trachomatis isolates with identified serovars/genovars and sequence types (ST) was used. Also considered were clonal relationships of sequence types (ST), defined with minimum spanning tree using BURST algorithms. In line with the aim of this study, concordance between typing methods was calculated using Simpson index and adjusted Rand and Wallace coefficients. Results are in context with the methods used for purpose of the study.

The reference is:

Babenko, D., Amirbekova, Z., Turmuhambetova, A., Sandle, T. and Chesca, A. (2016) In silico comparison serotyping and genotyping methods for Chlamydia trachomatis, Annals of Romanian Society for Cell Biology, Vol. XX, Issue 2, 2016, pp. 1 – 4

For further details, please contact Tim Sandle

Posted by Dr. Tim Sandle