A new article of interest:
A new regulatory consideration has arisen that affects pharmaceutical facilities of a certain vintage: the risks associated with the aging plant. In many more established areas of the world, pharmaceutical facilities are passing various time marks: thirty years, fifty years and even longer. As many pharmaceutical companies seek to establish manufacturing facilities for new product lines in emerging markets (China, Eastern Europe, Asia, for example) some of the more established plants in regions like North America and Europe begin to look older and possibly need more maintenance.
The reference is:
Sandle, T. (2016) Risk Consideration for Aging Pharmaceutical Facilities, Journal of Validation Technology, 22 (2): 11-20
Posted by Dr. Tim Sandle