Monday, 22 January 2018

Application of ISO 14644 Parts 1 and 2 for cleanroom contamination control

Cleanrooms are highly controlled environments, defined the air quality, and where certain physical and microbiological requirements need to be met.  Air quality is achieved through a combination of airborne particulate control, such as through High Efficiency Particulate Air (HEPA) filters; high fresh air rates (air movement and air changes); clean-up (or ‘recovery’) times; pressure differentials, which concerns air direction; temperature and humidity control (where necessary); cleaning and disinfection; and staff behaviors and gowning. The requirements for air quality, and the associated physical aspects designed to achieve this, are contained within the international standard ISO 14644.

To examine the requirements of Parts 1 and 2 of the standard in relation to contamination control in cleanrooms, Tim Sandle has written a chapter for Volume 8 of the ongoing Environmental Monitoring: A Comprehensive Handbook series.

Different types of cleanrooms require different levels of control to achieve the desired level of cleanliness. The required standard of cleanliness of a room will relate to the type of task performed in it and it follows that the more susceptible the product is to contamination, the better (“cleaner”) the standard that is accepted. The chapter explores this principle from the perspective of microbiological risk,

The reference is:

Sandle, T. (2017) Application of ISO 14644 Parts 1 and 2 for cleanroom contamination control. In Moldenhauer, J. (Ed.) Environmental Monitoring: A Comprehensive Handbook, Volume 8, DHI Publoshing / PDA, River Grove, IL, USA, pp3-22

Posted by Dr. Tim Sandle

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