Sunday, 29 July 2018

General Data on Cell Membrane and Membrane Traffic

Membrane trafficking refers to the mechanism through which proteins and other types of macromolecules become distributed throughout a cell. The trafficking also refers to the way that macromolecules, and pathogens, are released from the extracellular space. The activity of
membrane trafficking deploys membrane-bound vesicles as transport intermediaries. This transportation process can occur within different organelles within the same cell; or, alternatively, it can occur across the cell membrane in two directions: to and from the extracellular environment.

These are two basic pathways, depending upon the direction of movement: exocytosis (the outward pathway that carries material synthesized in the cytoplasm to the cell milieu) and endocytosis (the pathway which internalizes material from the environment to the inside of the cell). These pathways are part of the way a cell communication with its environment, a process that is critical for all tissue and organ function.

This short paper examines the latest theories relating to eukaryotic cell membranes around the fluid mosaic model (and the processes of exocytosis, endocytosis, phagocytosis, and transcytosis), and the implications that this model holds for biochemistry.


Sandle, T. and Chesca, A. (2018) General Data on Cell Membrane and Membrane Traffic, SF J Anal Biochem 1 (2): 1-3

The paper can be accessed via Research Gate

Posted by Dr. Tim Sandle

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