Cleanrooms
and clean areas must be regularly cleaned and disinfected. This is normally
undertaken using a detergent step, followed by the application of a
disinfectant. It may be necessary to remove the residue of the disinfectant
using water. Cleaning and disinfection should also extend to equipment.
Furthermore, with personnel, sanitization is important in relation to glove
hands.
In
relation to this, Tim Sandle has written an article for American Pharmaceutical Review which reviews the key points to
consider for the practical application of a cleaning and validation program within
a pharmaceutical facility, with a focus on disinfectant selection.
The
reference is:
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Pharmaceutical Microbiology Resources