A
new article of interest has been published:
Knowing
prevalent sexually transmitted bacterial infections, we can mention Chlamydia trachomatis as one of the most
important. For the purpose of the study, the genotyping methods have some
advances being more precise, compared to immunotyping. In this context, the
present study aims to compare phenotypic and genotypic methods for subspecies
identification of Chlamydia trachomatis in term of discriminatory power and
concordance. For analysis, a data table of Chlamydia trachomatis isolates with
identified serovars/genovars and sequence types (ST) was used. Also considered
were clonal relationships of sequence types (ST), defined with minimum spanning
tree using BURST algorithms. In line with the aim of this study, concordance
between typing methods was calculated using Simpson index and adjusted Rand and
Wallace coefficients. Results are in context with the methods used for purpose
of the study.
The
reference is:
Babenko,
D., Amirbekova, Z., Turmuhambetova, A., Sandle, T. and Chesca, A. (2016) In
silico comparison serotyping and genotyping methods for
Chlamydia trachomatis, Annals of Romanian
Society for Cell Biology, Vol. XX, Issue 2, 2016, pp. 1 – 4
Posted by Dr. Tim Sandle
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Pharmaceutical Microbiology