Tests for Antimicrobial Effectiveness

Tim Sandle has contributed a chapter to a new book about medical diagnosis. The abstract reads:

When a patient is infected with a bacterial infection understanding and administering the appropriate drug is of great importance. To select the appropriate medication, antimicrobials must be selected and their effectiveness demonstrated though controlled testing. Here, Antibiotic susceptibility testing (AST) is conducted to determine which antibiotic will be most successful in treating a bacterial infection in vivo. The detection of antimicrobial substances is also an important part of drug discovery. This chapter discusses the basis of the antimicrobial effectiveness test, as a mainstay of the clinical microbiology laboratory. The chapter also considers tests for preservative efficacy. Preservatives are added to some drug products in order to suppress any microbial growth that might occur once the product begins to be used by the consumer. The ability of these antimicrobial preservatives to inhibit or kill microorganisms is evaluated using the antimicrobial effectiveness test (AET).

Sandle, T, (2016) Tests for Antimicrobial Effectiveness, Chesca, A. and Cengiz, M. (Eds.) Theory and Practice for Medical Diagnosis, Lambert Academic Publishing, Germany, pp7-19

With this volume, we complete a successful international collaboration. with collaborators from IP Erasmus project entitled, “Classic and Modern Methods for Molecular Diagnostics in Human Pathology “,MDHP, coordinated from Faculty of Medicine, Transilvania University of Braşov, Romania, three years, from 2011 to 2013. Partners universities and project teachers, from different countries below. Radboud University Nijmegen, NL İstanbul University Cerrahpasa Medical Faculty and Istanbul Medical Faculty TR Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, SL University of Pardubice, CZ University of Medicine, Pecs, HU Université Claude Bernard Lyon I, FR University of Pharmacy and Medicine, Iuliu – Haţieganu Cluj- Napoca, RO University of Pharmacy and Medicine, Targu – Mureş, RO Beside the project, took part, as lecturer, proffessor Ilya Azizov from Karaganda Medical University, KZ Additional prestigious collaborators mentioned at the end but not the last, Dr. Tim Sandle PhD, Head of Microbiology at Bio Products Laboratory, UK. I would thank Dr. Sandle for his assessment for publishing this book.

Posted by Dr. Tim Sandle