New program to reduce animal testing
relating to toxicology in the U.S.
This strategic roadmap is a resource
to guide U.S. federal agencies and stakeholders seeking to adopt new approaches
to safety and risk assessment of chemicals and medical products that improve
human relevance and replace or reduce the use of animals. This document was
developed with input from members of 16 federal agencies, multiple interagency
workgroups, and input from the public. As such, it represents a consensus
perspective that does not necessarily reflect opinions or policy of any
specific agency or workgroup, and should not be taken as a commitment by any
federal agency.
Activities to implement the
strategic roadmap goals are already underway. ICCVAM workgroups will develop
detailed implementation plans to address roadmap goals, tailored to specific
toxicological endpoints of concern.
To expedite the use of 21st-century
science to protect and improve public health, federal agencies and stakeholders
will work together to build a new framework to enable development, establish
confidence in, and ensure use of new approaches to toxicity testing that
improve human health relevance and reduce or eliminate the need for testing in
animals. The successful development and implementation of these new approaches
will require coordinated efforts that address the three strategic goals
described below.
(1) Connect end users with the
developers of NAMs
(2) Foster the use of efficient,
flexible, and robust practices to establish confidence in new methods
(3) Encourage the adoption and use
of new methods and approaches by federal agencies and regulated industries
Posted by Dr. Tim Sandle