In
the past ten years there have been several advances in single-use sterile,
disposable technologies, such as bag chambers, connectors, tubing, filling
needle manifolds, and filter capsule, either as individual entities or complete
systems. These single-use systems have challenged the established cycle of
re-using equipment (primarily stainless steel) and which promises a new
paradigm for pharmaceutical manufacturing.
In
a new article Tim Sandle outlines a strategy for pharmaceutical companies
wishing to adopt, or increase their use of, single used sterile disposable
technologies.
Single-use
technologies include tubing, capsule filters, single-use ion exchange membrane
chromatography devices, single-use mixers, and bioreactors, product holding
sterile bags in place of stainless steel vessels (sterile fluid containment
bags), connection devices and sampling receptacles. This article considers the
advantages of implementing single-use technology and outlines a framework that
can be used as a strategy for the implementation process.”
The
reference is:
Sandle,
T. (2018) Strategy for the adoption of single-use technology, European Pharmaceutical Review, 23 (1): 43-45
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