Creating ‘smart’ microbial bionsensors: An interview with a Los Alamos National Laboratory researcher

New research shows that protein-based biosensors can detect the presence of a desired enzyme target and respond by physically lighting up and enabling researchers to immediately identify cells with increased overall enzyme yield.

The new approach, which comes from Los Alamos National Laboratory, can be translated to screening of metagenomic samples, rational enzyme design, or

directed evolution of known enzymes. The technology is adaptable to a single enzyme, or a pathway, or global optimization of an industrial strain.

Tim Sandle has conducted an interview with Dr. Ramesh Jha of the Los Alamos National Laboratory to discover more.

The reference is:

Sandle, T. (2019) Creating ‘smart’ microbial bionsensors: An interview with a Los Alamos National Laboratory researcher, Pharmig News, 75, pp2-3

For details, contact Tim Sandle

Posted by Dr. Tim Sandle, Pharmaceutical Microbiology