With biological tests all measurements susceptible to
variations in analytical conditions should be suitably controlled as far as is
practicable. Here the LAL assay has a relatively elevated level of variability
even for a biological assay. This variation derives from three principle
sources: reagents, product, and method / instrumentation. This article examines
some of the reasons for this variation in relation to the test and the test
reagents. The article also examines the coefficient of variation which is one
way to examine for test variation.
In relation to the LAL assay, Tim Sandle has written a paper
assessing assay control.
This article examines some of the reasons for this variation
in relation to the test and the test reagents. The article also examines the
coefficient of variation which is one way to examine for test variation.
The reference is:
For further details, please contact Tim Sandle
Posted by Dr. Tim Sandle, Pharmaceutical Microbiology
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