Wednesday 12 February 2014

Adopting Single-Use Systems

The adoption of single-use systems in biopharmaceutical production originated with the desire to minimize cleaning and associated validation. Before long, bioprocessors recognized the value of flexibility, reduced capital costs, and faster campaign turnaround times attainable through disposable bioprocess equipment. Single-use technologies have evolved from a supporting role for upstream operations (e.g., media storage and cell harvest) to near-complete platform processes that include all downstream processing steps except chromatography.

John Schmitz has written an informative overview of the technology for BioPharm International. The article can be viewed on-line here.

Posted by Tim Sandle

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