In a new study, Salmonella-infected mice that were given
antibiotics became sicker and began shedding far more bacteria in their feces
than they had before.
When the scientists gave oral antibiotics to mice infected with Salmonella typhimurium, a small minority
-- so called "superspreaders" that had been shedding high numbers of
salmonella in their feces for weeks -- remained healthy;
they were unaffected by either the disease or the antibiotic. The rest of the
mice got sicker instead of better and, oddly, started shedding like
superspreaders. The findings point to a reason for superspreaders' ability to
remain asymptomatic. They also pose ominous questions about the widespread,
routine use of sub-therapeutic doses of antibiotics in livestock.
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Posted by Tim Sandle
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