Insects can transmit viral diseases to
humans. Therefore, understanding how insects cope with viral infection, and
what immune mechanisms are triggered, can be important to stop diseases
transmission. In a new study, researchers now show that the entry route of the
virus changes how the insect host responds to it.
Using the fruit flies as a model of study,
researchers have discovered an immune mechanism that is specifically effective
when flies are infected through feeding.
When flies were fed with food containing
virus they would require an immune mechanism that had been described only to be
activated for infections caused by bacteria or fungi, the so called Toll
pathway.
Knowing better the host's responses upon
viral infection by different routes might also help to explain some biological
phenomena observed in nature. For example, the survival of honeybees
contaminated with virus seems to depend on the entry route of the virus. If
contaminated through bites of mites, the honeybees die, whereas if they receive
the virus from their progenitors, they can live.
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Posted by Tim Sandle
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