The
discovery of how a group of bacteria rapidly adapts to changing growth
conditions could have implications for future antibiotic development, according
to research at the University of Oxford and the University of York.
Gram-negative
bacteria have intricate
regulatory mechanisms
for ensuring they have the right complement of outer membrane proteins -- known
as OMPs -- for a particular habitat. But little is known about how OMPs are
replaced in the outer membrane when bacteria adapt to changes in their growth
conditions.
The
new research describes how bacteria are able to change the proteins in their
outer membrane and how this is intimately linked to the process of protein
insertion in the membrane.
For
details about the research, see:
Posted by Tim Sandle
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