Scientists
from the Berlin Institute of Health (BIH), Charité -- Universitätsmedizin
Berlin and the Thorax Clinic at Heidelberg University Hospital, whose
collaboration is taking place under the auspices of the German Center for Lung
Research (DZL), have examined samples from non-virus infected patients to
determine which cells of the lungs and bronchi are targets for novel
coronavirus (SARS-CoV-2) infection. They discovered that the receptor for this
coronavirus is abundantly expressed in certain progenitor cells. These cells
normally develop into respiratory tract cells lined with hair-like projections
called cilia that sweep mucus and bacteria out of the lungs.
60,000
single cells were sequenced
The
researchers discovered that certain progenitor cells in the bronchi are mainly
responsible for producing the coronavirus receptors. These progenitor cells
normally develop into respiratory tract cells lined with hair-like projections
called cilia that sweep mucus and bacteria out of the lungs.
See:
Posted by Dr. Tim Sandle, Pharmaceutical Microbiology Resources (http://www.pharmamicroresources.com/)
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