Thursday 26 January 2023

eBook: Proven Applications Using Variable Pathlength Spectroscopy

Image: CC BY-SA 3.0,

This eBook provides details and insight into using Slope Spectroscopy and the CTech™ SoloVPE® variable pathlength spectroscopy system. The SoloVPE® system provides a rapid, robust, and repeatable, non-disruptive concentration measurement method for proteins, plasmid DNA, and nucleic acid modalities. 

Articles in this eBook cover a variety of topics including viral filtration integrity, polysorbate UV-Vis spectral and slope analysis, how to measure Co-Oximetry parameters in bovine hemoglobin, accurately calculating the plasmid DNA purity ratio in human gene therapy products, techniques for real-time biomanufacturing process monitoring, and the application of in-line variable pathlength chromatography for high-concentration oligonucleotide solutions.



To access, see: eBook

Posted by Dr. Tim Sandle, Pharmaceutical Microbiology Resources (

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