Biofilms
are problematic to pharmaceutical water systems. If a biofilm develops then an
out-of-control situation is likely to emerge. Such a situation can often only
be detected from point-of-use samples and since several excursions are required
to alert of the probability of a biofilm, the biofilm will most likely have
become significantly established at this point in time. This article assesses
biofilms and pharmaceutical water systems, considering prevention and control
measures; looking at what can be meaningfully gleaned from monitoring; and
measures required to address biofilms.
Tim
Sandle has written an article for American Pharmaceutical Review. The reference
is:
Sandle,
T. (2017) The Problem of Biofilms and Pharmaceutical Water Systems, American Pharmaceutical Review, 20 (7): http://www.americanpharmaceuticalreview.com/Featured-Articles/345440-The-Problem-of-Biofilms-and-Pharmaceutical-Water-Systems/
Posted by Dr. Tim Sandle
This is really good content about biofilm formation and the risks presented to pharmaceutical facilities.
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