Scientists have successful developed a so-termed ‘poisoned arrow’ designed to defeat antibiotic-resistant bacteria. Such developments are critical in the battle against antimicrobial resistant organisms. The success is based on a dual-mechanism.
Ever since their discovery some decades ago, antimicrobial agents particularly antibiotics have saved mankind from the morbidity and mortality of innumerable infectious diseases and/or pathogenic agents even till date. However, due natural resistance; mis-prescribing; overuse; and arguably mis-use (in the case of administering antibiotics to farm animals), many pathogenic organisms have developed resistance to the most common antimicrobials, creating a pressing global need for alternatives.
This article looks at three areas of research where antimicrobials are being innovated in novel ways.
Reference:
Sandle, T. (2021) Firing an arrow with new antibiotics, Pharmig News, Issue 82, pp16-8
Posted by Dr. Tim Sandle, Pharmaceutical Microbiology Resources (http://www.pharmamicroresources.com/)
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