Feeling the pressure: Cleanroom design and pressure differentials

 

Maintaining pressure differentials between cleanrooms of different grades where there are openings (such as doors leading to airlocks or transfer hatches) is one of the important contamination control measures. 

Differential pressure ((DP or ∆P)) is a measure of pressure where the reading and reference values are variable. Differential pressure is calculated by subtracting one of these values from the other. The difference is the pressure gradient.

This week’s article looks at pressure differentials, the risks of negative pressure, the minimum pressures required for contamination control and the effects that can occur when doors are opened.  

See: https://www.linkedin.com/pulse/feeling-pressure-cleanroom-design-differentials-tim-7xg0e/?trackingId=tV9W5uNsQKuAEFC6etFgdQ%3D%3D

Posted by Dr. Tim Sandle, Pharmaceutical Microbiology Resources (http://www.pharmamicroresources.com/)