Thursday, 21 February 2013

Cleanrooms and Air Quality – A Risk-Based Approach


Cleanrooms are highly controlled environments where the air quality is monitored to ensure the extreme standards of cleanliness required for the manufacture of pharmaceutical, electronic, and healthcare goods. These stringent standards usually require high fresh air rates, extensive filtering, temperature, and humidity control - all of which results in increased energy usage.

Protection from uncontrolled ingress of external ambient air is achieved by creating a pressure differential between the cleanroom and its surroundings. Contamination control is the primary consideration in cleanroom design; however, the relationships between contamination control and airflow are not well understood. Contaminants such as particles or microbes are primarily introduced to cleanrooms by people, although processes in cleanrooms may also introduce contamination. During periods of inactivity or when people are not present, it is possible to reduce airflow and maintain cleanliness conditions.

In relation to the risk assessment of cleanrooms, Tim Sandle has written a free-to-view online paper. Access it here: Sandle cleanrooms.

Posted by Tim Sandle