Bioengineers
at the University of California, San Diego have used the genomic sequences of
55 E. coli strains to reconstruct the
metabolic sequenced for each strain. These reconstructions predict the kind of
environment where each strain will thrive.
The
reconstructions map out all the genes, reactions and products of metabolism for
each strain and allow the researchers to probe their coordinated functionality.
Each strain's metabolic capabilities, the researchers discovered, correspond to
specific environmental niches. Commensal or "friendly" E. coli strains also can be
distinguished from pathogenic strains using this technique.
Posted by Tim Sandle
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