Tuesday, 9 May 2017

Pharmeuropa 29.1


Pharmeuropa is a free online EDQM publication. Draft monographs are published in Pharmeuropa for public enquiry, which lasts for three months.

Draft Monographs and General Texts for Comment.

2.3.2    Identification of fatty oils by thin-layer chromatography

Method A: chromatogram of hydrogenated arachis oil added.

2.2.32  Loss on drying

Due to its toxicity, the replacement of diphosphorus pentoxide with a molecular sieve is proposed.  The introduction of a standardised amount of desiccant to be used will also help to alleviate to a certain extent that variability.

The conditions of ‘high vacuum’, which were reported to be difficult to achieve with available instruments, are proposed for deletion; this would trigger a revision of the concerned monographs in due time.  Additional clarifications are proposed throughout the general chapter.


 

Posted by Dr. Tim Sandle