ABC
Transporters are proteins that are embedded in the cell membrane and facilitate
the transport across cellular barriers not only of an almost unlimited variety
of toxic substances, but also of substances that are essential for life. They
also play a role in the development of antibiotic resistance. A research group
has now succeeded in elucidating the detailed structure of this transporter.
For details
see:
JungMin Kim,
Shenping Wu, Thomas M. Tomasiak, Claudia Mergel, Michael B. Winter, Sebastian
B. Stiller, Yaneth Robles-Colmanares, Robert M. Stroud, Robert Tampé, Charles
S. Craik, Yifan Cheng. Subnanometre-resolution electron cryomicroscopy
structure of a heterodimeric ABC exporter. Nature, 2014; DOI: 10.1038/nature13872
Posted by Tim Sandle
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