Wednesday 16 June 2021

Limited Ability: Understanding the Concerns Around Microbial Methods and Sampling


Microbiological methods are less precise than analytical ones, even with the advent of rapid microbiological methods. This is because our ability to detect specifically is limited. Microbiological samples are often less representative of what is actually present in a sample, reflecting the issue of microbial culturability. Finally, microbial samples are generally less accurate than chemical ones, due to the variations with the distribution of microorganisms in the environment.

In this article, the reasons for the limitations of method, specificity, and distribution are briefly considered. The aim is to present background information about the limitations of microbial data within pharmaceuticals and healthcare, for microbiologists and non-microbiologists alike.

 To access Tim Sandle's new article on microbiololgical methods, see: IVT

Posted by Dr. Tim Sandle, Pharmaceutical Microbiology Resources (

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