Monday 16 October 2023

Direct flow cartridge filtration for sterile products processing


Filtration is a means of sterilising fluids (liquids or gases) through the removal, rather than the destruction or inactivation, of microorganisms. The design, construction and media used in the direct flow filtration of fluids or gases to provide sterile products represents a critical step. Membrane filters for sterile filtration are generally composed of microporous polymeric materials such as polyethersulphone (PES), polyvinylidene fluoride (PVDF), polypropylene, polysulphone and polytetrafluoroethylene (PTFE) each with its own characteristics and suitability for liquid or gas filtration.



This article looks at the essential requirements for the use of filters for sterile applications.


Sandle, T. (2023) Direct flow cartridge filtration for sterile products processing, Pharmig News, Issue 90, pp2-6


Posted by Dr. Tim Sandle, Pharmaceutical Microbiology Resources (

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