Monday, 3 March 2014

The influence of the gut microbiota on obesity and insulin resistance

We live with millions of microorganisms and these bacteria have a profound impact on host physiology. Microbial-responsive signaling by host cells affects metabolic, neurological, inflammatory, immunologic, and host defense functions.

There is tantalizing evidence indicating that the gut microbiota plays a significant role in the development of obesity, obesity-associated inflammation, and insulin resistance. An altered gut microbiota has been associated with obesity and diabetes (Diabetes. 2014 Jan 15). In addition, increased levels of circulating bacteria or bacterial products are associated with insulin resistance.

Posted by Tim Sandle