We
live with millions of microorganisms and these bacteria have a profound impact
on host physiology. Microbial-responsive signaling by host cells affects
metabolic, neurological, inflammatory, immunologic, and host defense functions.
There
is tantalizing evidence indicating that the gut microbiota plays a significant
role in the development of obesity, obesity-associated inflammation, and
insulin resistance. An altered gut microbiota has been associated with obesity
and diabetes (Diabetes. 2014 Jan 15). In addition, increased levels of
circulating bacteria or bacterial products are associated with insulin
resistance.
Posted by Tim Sandle
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Pharmaceutical Microbiology Resources