β-Glucans
(beta-glucans) are polysaccharides of D-glucose monomers linked by β-glycosidic
bonds. Glucans are important because they can react with certain lysates and
cause interference with the LAL test. Furthermore, glucans can, in certain
circumstances, cause physiological effects in humans (β-glucans are known as
“biological response modifiers” because of their ability to activate the immune
system).
To
discuss the implications on both the LAL test and in relation to pharmaceutical
products, Tim Sandle has written an article for the
American Pharmaceutical Review. The article has been published as a special
supplement ‘Further Pharmaceutical Microbiology’.
The
reference is:
Posted by Tim Sandle
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Pharmaceutical Microbiology Resources