Antibiotic Resistance Among Foodborne-Illness Germs a Mixed Bag: CDC

Report found reduced resistance to treatments with some bugs, more resistance among others

"Our latest data show some progress in reducing resistance among some germs that make people sick, but unfortunately we're also seeing greater resistance in some pathogens, like certain types of salmonella," Dr. Robert Tauxe, deputy director of the division of foodborne, waterborne and environmental diseases at the U.S. Centers for Disease Control and Prevention, said in an agency news release.TUESDAY, July 1, 2014 (HealthDay News) -- There's good news and bad news about antibiotic resistance among the germs that cause foodborne illnesses, a new U.S. government report released Tuesday shows.

Each year, antibiotic-resistant infections from foodborne germs cause about 430,000 illnesses in the United States, according to the CDC.

The agency's latest data, from 2012, show that multidrug-resistant salmonella, which causes about 100,000 illnesses a year, decreased during the past 10 years and resistance to two important types of antibiotics -- cephalosporins and fluoroquinolones -- remained low.

However, the rate of resistance to quinolone drugs in Salmonella typhi -- which causes typhoid fever -- rose to 68 percent in 2012. This means that this class of drugs, one of the most common treatments for typhoid fever, may no longer be effective.

The CDC also said that about 20 percent of Salmonella Heidelberg infections were resistant to the cephalosporin drug ceftriaxone. S. Heidelberg has been linked to recent outbreaks of illness associated with poultry.

Ceftriaxone resistance makes severe salmonella infections harder to treat, especially in children, the CDC noted.

Among the other findings:

• Campylobacter resistance to the antibiotic ciprofloxacin remained at 25 percent, despite a 2005 ban on the use of the antibiotic enrofloxacin in poultry. Ciprofloxacin and enrofloxacin are both fluoroquinolone antibiotics.
• Shigella resistance to ciprofloxacin (2 percent) and azithromycin (4 percent) increased, but no strains were resistant to both drugs.
• Resistance to fluoroquinolones remained low. However, 50 percent of infections resistant to the fluoroquinolone drug nalidixic acid were caused by Salmonella enteritidis, the most common salmonella type.

Resistance to nalidixic acid -- used in laboratory testing for resistance -- is related to decreased susceptibility to a widely used fluoroquinolone drug ciprofloxacin, the CDC said in its release.

Many of the nalidixic acid-resistant Salmonella enteritidis infections among Americans are acquired when they travel to other countries.

SOURCE: U.S. Centers for Disease Control and Prevention, news release, July 1, 2014 (thanks to Brian Mathews for the story tip)

Posted by Tim Sandle