Control
of airborne and surface microorganisms and airborne particles in a cleanroom is
achieved through the physical operation of the heating, ventilation, and air
conditioning system and cleaning and disinfection techniques.
Even
with these factors taken into account, contamination can still occur. One area
of concern is the entry of personnel2 and the movement of equipment into and
out of cleanrooms.3 Traditional ways to control these activities have centered
on gowning techniques and the cleaning of equipment. To accomplish this, cleanroom
mats are frequently used to remove particles from footwear and from trolley
wheels.
Research
undertaken at an independent laboratory evaluates the performance of temporary
adhesive mats and semi-permanent polymeric flooring in retaining contamination
from footwear, and particle generation from removing layers of the adhesive
mats.
Posted by Dr. Tim Sandle
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Pharmaceutical Microbiology Resources