Monday 8 February 2016

Microbiological Identification with MALDI-TOF MS

Matrix Assisted Laser Desorption/Ionization-Time Of Flight (MALDI-TOF) mass spectrometry has been developed as a microbiological identification method and it is becoming commonplace in many laboratories. In a review article, Tim Sandle considers the strengths and weaknesses of MALD-TOF and considers its practical application. The paper has been published in the Journal of Validation Technology.

The abstract reads: “This paper discusses the MALDI-TOF technology and outlines the advantages and disadvantages with the system. Microbial identification plays an important role in pharmaceutical processing. Microbial identification can be defined as "microbial characterization by a limited spectrum of tests pre-chosen and appropriate to the problem being studied.”

For a copy, please contact Tim Sandle

The reference is:

Sandle, T. (2015) Microbiological Identification with MALDI-TOF MS, Journal of Validation Technology, 21 (3): 1-10 at:

Posted by Dr. Tim Sandle

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