The performance of a cleanroom is defined by a set of complex interactions between the airflow, sources of contamination and heat, position of vents, exhausts, and any objects occupying the space. Consequently, changes to any of these elements will potentially affect the operation of the cleanroom and could invalidate aspects of the room design.
With cleanrooms used in the pharmaceutical industry, there are
additional considerations aimed at minimizing contamination. These are centered
on the idea that cleanrooms should be constructed in a way which makes them
easy to clean and disinfect.
Posted by Dr. Tim Sandle
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Pharmaceutical Microbiology Resources