Tuesday, 24 February 2026

Shedding light on the dark proteome


New technology feature

 

Proteins drive biology and some of our most devastating diseases, but existing tools can barely measure 8% of them. Nautilus Biotechnology has unveiled Voyager to shed light on this dark proteome - for good. 

 

Voyager is designed to be a standard benchtop instrument that features Nautilus’ Iterative Mapping technology for rapidly and simultaneously measuring up to 10 billion intact proteins per experiment. Leading researchers are already field-testing it and finding: 

 

  1. High accuracy, precision, and reproducibility in studies looking at proteins (the targets of 95% of all FDA-approved drugs)
  2. Voyager is the only tech out there that can measure intact proteins at this scale. No breaking down proteins
  3. Novel insights into biomarkers and proteoform biology, starting with neurodegenerative diseases (e.g. Alzheimer’s tau, Parkinson’s alpha-synuclein)

 

Posted by Dr. Tim Sandle, Pharmaceutical Microbiology Resources (http://www.pharmamicroresources.com/)

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